Does MACITENTAN Cause Hepatic failure? 98 Reports in FDA Database

Q: Does MACITENTAN cause Hepatic failure?

98 reports of Hepatic failure have been filed with the FDA for MACITENTAN, representing 0.2% of all MACITENTAN adverse event reports.

Q: How dangerous is Hepatic failure from MACITENTAN?

Of 98 reports, 64 (65.3%) resulted in death and 78 required hospitalization.

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According to the FDA Adverse Event Reporting System (FAERS), 98 reports of Hepatic failure have been filed in association with MACITENTAN (OPSYNVI). This represents 0.2% of all adverse event reports for MACITENTAN.

Reports of Hepatic failure with MACITENTAN

0.2%

of all MACITENTAN reports

Deaths

Hospitalizations

How Dangerous Is Hepatic failure From MACITENTAN?

Of the 98 reports, 64 (65.3%) resulted in death, 78 (79.6%) required hospitalization, and 8 (8.2%) were considered life-threatening.

Is Hepatic failure Listed in the Official Label?

This adverse event is not currently listed in the official FDA drug label for MACITENTAN. However, 98 reports have been filed with the FAERS database.

What Other Side Effects Does MACITENTAN Cause?

Dyspnoea (8,315) Death (5,864) Headache (4,856) Diarrhoea (3,669) Pneumonia (3,531) Nausea (3,463) Hospitalisation (3,414) Fatigue (3,172) Fluid retention (2,861) Dizziness (2,704)

What Other Drugs Cause Hepatic failure?

ACETAMINOPHEN (1,392) RIBAVIRIN (888) CYCLOPHOSPHAMIDE (629) METHOTREXATE (598) BEVACIZUMAB (558) SOFOSBUVIR (525) RITUXIMAB (513) VINCRISTINE (468) DOXORUBICIN (462) PREDNISOLONE (425)

Which MACITENTAN Alternatives Have Lower Hepatic failure Risk?

MACITENTAN vs MACITENTAN\TADALAFIL MACITENTAN vs MAGNESIUM MACITENTAN vs MAGNESIUM ASPARTATE MACITENTAN vs MAGNESIUM ASPARTATE\POTASSIUM ASPARTATE MACITENTAN vs MAGNESIUM HYDROXIDE

MACITENTAN Full Profile All Hepatic failure Reports All Drugs Causing Hepatic failure MACITENTAN Demographics