Does MELPHALAN Cause Cardiac failure? 177 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 177 reports of Cardiac failure have been filed in association with MELPHALAN (Melphalan Hydrochloride). This represents 1.1% of all adverse event reports for MELPHALAN.
177
Reports of Cardiac failure with MELPHALAN
1.1%
of all MELPHALAN reports
60
Deaths
88
Hospitalizations
How Dangerous Is Cardiac failure From MELPHALAN?
Of the 177 reports, 60 (33.9%) resulted in death, 88 (49.7%) required hospitalization, and 25 (14.1%) were considered life-threatening.
Is Cardiac failure Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for MELPHALAN. However, 177 reports have been filed with the FAERS database.
What Other Side Effects Does MELPHALAN Cause?
Off label use (2,002)
Febrile neutropenia (931)
Drug ineffective (853)
Neutropenia (810)
Mucosal inflammation (804)
Plasma cell myeloma (781)
Product use in unapproved indication (765)
Thrombocytopenia (701)
Diarrhoea (698)
Pyrexia (667)
What Other Drugs Cause Cardiac failure?
SACUBITRIL\VALSARTAN (4,504)
FUROSEMIDE (1,841)
APIXABAN (1,575)
CYCLOPHOSPHAMIDE (1,514)
DOXORUBICIN (1,367)
ADALIMUMAB (1,278)
DEXAMETHASONE (1,271)
TREPROSTINIL (1,168)
BISOPROLOL (1,159)
LENALIDOMIDE (1,115)
Which MELPHALAN Alternatives Have Lower Cardiac failure Risk?
MELPHALAN vs MEMANTINE
MELPHALAN vs MENINGOCOCCAL GROUP B VACCINE
MELPHALAN vs MENINGOCOCCAL POLYSACCHARIDE VACCINE A\NEISSERIA MENINGITIDIS GROUP A CAPSULAR POLYSACCHARIDE ANTIGEN
MELPHALAN vs MENOTROPINS
MELPHALAN vs MENTHOL