Does MELPHALAN Cause Second primary malignancy? 239 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 239 reports of Second primary malignancy have been filed in association with MELPHALAN (Melphalan Hydrochloride). This represents 1.5% of all adverse event reports for MELPHALAN.
239
Reports of Second primary malignancy with MELPHALAN
1.5%
of all MELPHALAN reports
111
Deaths
84
Hospitalizations
How Dangerous Is Second primary malignancy From MELPHALAN?
Of the 239 reports, 111 (46.4%) resulted in death, 84 (35.1%) required hospitalization, and 16 (6.7%) were considered life-threatening.
Is Second primary malignancy Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for MELPHALAN. However, 239 reports have been filed with the FAERS database.
What Other Side Effects Does MELPHALAN Cause?
Off label use (2,002)
Febrile neutropenia (931)
Drug ineffective (853)
Neutropenia (810)
Mucosal inflammation (804)
Plasma cell myeloma (781)
Product use in unapproved indication (765)
Thrombocytopenia (701)
Diarrhoea (698)
Pyrexia (667)
What Other Drugs Cause Second primary malignancy?
CYCLOPHOSPHAMIDE (1,247)
DOXORUBICIN (1,151)
VINCRISTINE (908)
IMATINIB (763)
PALBOCICLIB (658)
RITUXIMAB (646)
RUXOLITINIB (611)
ETOPOSIDE (573)
PREDNISONE (517)
OCTREOTIDE (496)
Which MELPHALAN Alternatives Have Lower Second primary malignancy Risk?
MELPHALAN vs MEMANTINE
MELPHALAN vs MENINGOCOCCAL GROUP B VACCINE
MELPHALAN vs MENINGOCOCCAL POLYSACCHARIDE VACCINE A\NEISSERIA MENINGITIDIS GROUP A CAPSULAR POLYSACCHARIDE ANTIGEN
MELPHALAN vs MENOTROPINS
MELPHALAN vs MENTHOL