Does MEPOLIZUMAB Cause Osteonecrosis? 37 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 37 reports of Osteonecrosis have been filed in association with MEPOLIZUMAB (Nucala). This represents 0.1% of all adverse event reports for MEPOLIZUMAB.
37
Reports of Osteonecrosis with MEPOLIZUMAB
0.1%
of all MEPOLIZUMAB reports
0
Deaths
26
Hospitalizations
How Dangerous Is Osteonecrosis From MEPOLIZUMAB?
Of the 37 reports, 26 (70.3%) required hospitalization.
Is Osteonecrosis Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for MEPOLIZUMAB. However, 37 reports have been filed with the FAERS database.
What Other Side Effects Does MEPOLIZUMAB Cause?
Asthma (11,033)
Dyspnoea (9,192)
Wheezing (6,093)
Product dose omission issue (5,873)
Cough (4,577)
Pneumonia (4,107)
Therapeutic product effect incomplete (4,106)
Drug ineffective (3,880)
Loss of personal independence in daily activities (3,566)
Fatigue (2,656)
What Other Drugs Cause Osteonecrosis?
EMTRICITABINE\TENOFOVIR DISOPROXIL (8,935)
TENOFOVIR DISOPROXIL (7,182)
EFAVIRENZ\EMTRICITABINE\TENOFOVIR DISOPROXIL (4,338)
COBICISTAT\ELVITEGRAVIR\EMTRICITABINE\TENOFOVIR DISOPROXIL (2,081)
EMTRICITABINE\RILPIVIRINE\TENOFOVIR DISOPROXIL (1,492)
PREDNISONE (779)
PREDNISOLONE (711)
DENOSUMAB (567)
METHOTREXATE (563)
DEXAMETHASONE (531)
Which MEPOLIZUMAB Alternatives Have Lower Osteonecrosis Risk?
MEPOLIZUMAB vs MEPROBAMATE
MEPOLIZUMAB vs MERCAPTOPURINE
MEPOLIZUMAB vs MEROPENEM
MEPOLIZUMAB vs MEROPENEM ANHYDROUS
MEPOLIZUMAB vs MESALAMINE