Does MESNA Cause Leukopenia? 47 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 47 reports of Leukopenia have been filed in association with MESNA (mesna). This represents 1.0% of all adverse event reports for MESNA.
47
Reports of Leukopenia with MESNA
1.0%
of all MESNA reports
12
Deaths
12
Hospitalizations
How Dangerous Is Leukopenia From MESNA?
Of the 47 reports, 12 (25.5%) resulted in death, 12 (25.5%) required hospitalization, and 9 (19.1%) were considered life-threatening.
Is Leukopenia Listed in the Official Label?
Yes, Leukopenia is listed as a known adverse reaction in the official FDA drug label for MESNA.
What Other Side Effects Does MESNA Cause?
Febrile neutropenia (707)
Pyrexia (352)
Off label use (299)
Cystitis haemorrhagic (294)
Disease progression (273)
Neutropenia (238)
Encephalopathy (226)
Vomiting (200)
Death (184)
Pancytopenia (179)
What Other Drugs Cause Leukopenia?
METHOTREXATE (2,694)
CYCLOPHOSPHAMIDE (2,482)
RITUXIMAB (2,191)
CLOZAPINE (2,036)
PREDNISONE (1,725)
DOXORUBICIN (1,696)
PACLITAXEL (1,649)
CARBOPLATIN (1,624)
DEXAMETHASONE (1,542)
MYCOPHENOLATE MOFETIL (1,491)
Which MESNA Alternatives Have Lower Leukopenia Risk?
MESNA vs METAMIZOLE
MESNA vs METARAMINOL
MESNA vs METAXALONE
MESNA vs METFORMIN
MESNA vs METFORMIN\PIOGLITAZONE