Does METFORMIN Cause Osteoarthritis? 445 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 445 reports of Osteoarthritis have been filed in association with METFORMIN (Metformin Hydrochloride). This represents 0.5% of all adverse event reports for METFORMIN.
445
Reports of Osteoarthritis with METFORMIN
0.5%
of all METFORMIN reports
146
Deaths
252
Hospitalizations
How Dangerous Is Osteoarthritis From METFORMIN?
Of the 445 reports, 146 (32.8%) resulted in death, 252 (56.6%) required hospitalization, and 144 (32.4%) were considered life-threatening.
Is Osteoarthritis Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for METFORMIN. However, 445 reports have been filed with the FAERS database.
What Other Side Effects Does METFORMIN Cause?
Lactic acidosis (16,316)
Acute kidney injury (11,361)
Diarrhoea (7,679)
Toxicity to various agents (5,669)
Metabolic acidosis (5,236)
Hypoglycaemia (5,047)
Drug ineffective (4,991)
Nausea (4,915)
Vomiting (4,624)
Blood glucose increased (4,038)
What Other Drugs Cause Osteoarthritis?
ADALIMUMAB (8,893)
METHOTREXATE (4,979)
ETANERCEPT (4,124)
ABATACEPT (3,158)
RITUXIMAB (3,145)
LEFLUNOMIDE (3,131)
TOCILIZUMAB (2,986)
ALENDRONATE (2,851)
TOFACITINIB (2,831)
HYDROXYCHLOROQUINE (2,717)
Which METFORMIN Alternatives Have Lower Osteoarthritis Risk?
METFORMIN vs METFORMIN\PIOGLITAZONE
METFORMIN vs METFORMIN\ROSIGLITAZONE
METFORMIN vs METFORMIN\SAXAGLIPTIN
METFORMIN vs METFORMIN\SITAGLIPTIN
METFORMIN vs METFORMIN\VILDAGLIPTIN