Does METHADONE Cause Hepatic failure? 24 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 24 reports of Hepatic failure have been filed in association with METHADONE (METHADONE HYDROCHLORIDE). This represents 0.1% of all adverse event reports for METHADONE.
24
Reports of Hepatic failure with METHADONE
0.1%
of all METHADONE reports
14
Deaths
17
Hospitalizations
How Dangerous Is Hepatic failure From METHADONE?
Of the 24 reports, 14 (58.3%) resulted in death, 17 (70.8%) required hospitalization, and 3 (12.5%) were considered life-threatening.
Is Hepatic failure Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for METHADONE. However, 24 reports have been filed with the FAERS database.
What Other Side Effects Does METHADONE Cause?
Drug dependence (5,739)
Toxicity to various agents (4,586)
Drug abuse (4,480)
Overdose (3,472)
Pain (2,754)
Death (2,716)
Emotional distress (2,388)
Drug withdrawal syndrome (2,127)
Foetal exposure during pregnancy (1,759)
Drug withdrawal syndrome neonatal (1,458)
What Other Drugs Cause Hepatic failure?
ACETAMINOPHEN (1,392)
RIBAVIRIN (888)
CYCLOPHOSPHAMIDE (629)
METHOTREXATE (598)
BEVACIZUMAB (558)
SOFOSBUVIR (525)
RITUXIMAB (513)
VINCRISTINE (468)
DOXORUBICIN (462)
PREDNISOLONE (425)
Which METHADONE Alternatives Have Lower Hepatic failure Risk?
METHADONE vs METHAMPHETAMINE
METHADONE vs METHENAMINE HIPPURATE
METHADONE vs METHIMAZOLE
METHADONE vs METHOCARBAMOL
METHADONE vs METHOHEXITAL