MIDOSTAURIN for Chemotherapy: Side Effects & Safety Data
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There are 7 adverse event reports in the FDA FAERS database where MIDOSTAURIN was used for Chemotherapy.
Most Reported Side Effects for MIDOSTAURIN
| Side Effect | Reports | % | Deaths | Hosp. |
|---|---|---|---|---|
| Death | 397 | 13.3% | 396 | 22 |
| Nausea | 252 | 8.4% | 21 | 50 |
| Febrile neutropenia | 223 | 7.5% | 33 | 90 |
| Diarrhoea | 194 | 6.5% | 29 | 59 |
| Pyrexia | 188 | 6.3% | 25 | 90 |
| Acute myeloid leukaemia recurrent | 171 | 5.7% | 29 | 14 |
| Pancytopenia | 152 | 5.1% | 11 | 25 |
| Vomiting | 152 | 5.1% | 25 | 45 |
| Drug ineffective | 151 | 5.1% | 18 | 13 |
| Thrombocytopenia | 140 | 4.7% | 17 | 37 |
| Neutropenia | 136 | 4.5% | 15 | 25 |
| Pneumonia | 128 | 4.3% | 47 | 74 |
| Bone marrow failure | 109 | 3.6% | 13 | 14 |
| Sepsis | 106 | 3.5% | 54 | 50 |
| Anaemia | 97 | 3.2% | 17 | 33 |
Other Indications for MIDOSTAURIN
Acute myeloid leukaemia (1,653)
Product used for unknown indication (688)
Systemic mastocytosis (270)
Myelodysplastic syndrome (45)
Mastocytic leukaemia (36)
Mastocytosis (36)
Leukaemia (28)
Flt3 gene mutation (16)
Acute leukaemia (15)
Myeloid leukaemia (14)
Other Drugs Used for Chemotherapy
CYCLOPHOSPHAMIDE (3,372)
DOCETAXEL (2,134)
CARBOPLATIN (1,902)
DOXORUBICIN (1,756)
VINCRISTINE (1,743)
PACLITAXEL (1,425)
OXALIPLATIN (1,423)
METHOTREXATE (1,380)
CYTARABINE (1,355)
ETOPOSIDE (1,246)