MITOXANTRONE for Bone marrow conditioning regimen: Side Effects & Safety Data
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There are 30 adverse event reports in the FDA FAERS database where MITOXANTRONE was used for Bone marrow conditioning regimen.
Most Reported Side Effects for MITOXANTRONE
| Side Effect | Reports | % | Deaths | Hosp. |
|---|---|---|---|---|
| Febrile neutropenia | 668 | 16.0% | 87 | 403 |
| Off label use | 368 | 8.8% | 82 | 142 |
| Neutropenia | 296 | 7.1% | 76 | 144 |
| Drug ineffective | 293 | 7.0% | 79 | 119 |
| Thrombocytopenia | 256 | 6.1% | 66 | 128 |
| Sepsis | 240 | 5.8% | 94 | 98 |
| Pyrexia | 214 | 5.1% | 46 | 125 |
| Product use in unapproved indication | 177 | 4.3% | 53 | 58 |
| Disease progression | 173 | 4.2% | 58 | 42 |
| Acute myeloid leukaemia | 167 | 4.0% | 78 | 43 |
| Pneumonia | 157 | 3.8% | 76 | 71 |
| Infection | 153 | 3.7% | 72 | 37 |
| Pancytopenia | 148 | 3.6% | 24 | 57 |
| Myelodysplastic syndrome | 139 | 3.3% | 35 | 25 |
| Septic shock | 133 | 3.2% | 57 | 98 |
Other Indications for MITOXANTRONE
Acute myeloid leukaemia (1,248)
Acute lymphocytic leukaemia (414)
Diffuse large b-cell lymphoma (201)
Product used for unknown indication (183)
Acute promyelocytic leukaemia (158)
B-cell lymphoma (125)
Multiple sclerosis (112)
Non-hodgkin's lymphoma (104)
B-cell type acute leukaemia (101)
Acute lymphocytic leukaemia recurrent (89)
Other Drugs Used for Bone marrow conditioning regimen
FLUDARABINE (6,080)
BUSULFAN (4,669)
CYCLOPHOSPHAMIDE (4,485)
MELPHALAN (2,368)
LAPINE T-LYMPHOCYTE IMMUNE GLOBULIN (1,884)
THIOTEPA (1,551)
ALEMTUZUMAB (1,122)
ETOPOSIDE (936)
CYTARABINE (833)
THYMOCYTE IMMUNE GLOBULIN NOS (742)