Does MITOXANTRONE Cause Aplasia? 19 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 19 reports of Aplasia have been filed in association with MITOXANTRONE (mitoXANTRONE). This represents 0.5% of all adverse event reports for MITOXANTRONE.
19
Reports of Aplasia with MITOXANTRONE
0.5%
of all MITOXANTRONE reports
6
Deaths
10
Hospitalizations
How Dangerous Is Aplasia From MITOXANTRONE?
Of the 19 reports, 6 (31.6%) resulted in death, 10 (52.6%) required hospitalization, and 2 (10.5%) were considered life-threatening.
Is Aplasia Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for MITOXANTRONE. However, 19 reports have been filed with the FAERS database.
What Other Side Effects Does MITOXANTRONE Cause?
Febrile neutropenia (668)
Off label use (368)
Neutropenia (296)
Drug ineffective (293)
Thrombocytopenia (256)
Sepsis (240)
Pyrexia (214)
Product use in unapproved indication (177)
Disease progression (173)
Acute myeloid leukaemia (167)
What Other Drugs Cause Aplasia?
CYTARABINE (229)
ETOPOSIDE (217)
CYCLOPHOSPHAMIDE (213)
METHOTREXATE (199)
VINCRISTINE (167)
DOXORUBICIN (144)
CARBOPLATIN (136)
DEXAMETHASONE (129)
RITUXIMAB (98)
IFOSFAMIDE (88)
Which MITOXANTRONE Alternatives Have Lower Aplasia Risk?
MITOXANTRONE vs MITRAGYNINE\HERBALS
MITOXANTRONE vs MIZORIBINE
MITOXANTRONE vs MOBOCERTINIB
MITOXANTRONE vs MOCLOBEMIDE
MITOXANTRONE vs MODAFINIL