Does MITOXANTRONE Cause Differentiation syndrome? 5 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 5 reports of Differentiation syndrome have been filed in association with MITOXANTRONE (mitoXANTRONE). This represents 0.1% of all adverse event reports for MITOXANTRONE.
5
Reports of Differentiation syndrome with MITOXANTRONE
0.1%
of all MITOXANTRONE reports
3
Deaths
0
Hospitalizations
How Dangerous Is Differentiation syndrome From MITOXANTRONE?
Of the 5 reports, 3 (60.0%) resulted in death, and 2 (40.0%) were considered life-threatening.
Is Differentiation syndrome Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for MITOXANTRONE. However, 5 reports have been filed with the FAERS database.
What Other Side Effects Does MITOXANTRONE Cause?
Febrile neutropenia (668)
Off label use (368)
Neutropenia (296)
Drug ineffective (293)
Thrombocytopenia (256)
Sepsis (240)
Pyrexia (214)
Product use in unapproved indication (177)
Disease progression (173)
Acute myeloid leukaemia (167)
What Other Drugs Cause Differentiation syndrome?
TRETINOIN (251)
ARSENIC TRIOXIDE (180)
ENASIDENIB (102)
GILTERITINIB (80)
IVOSIDENIB (80)
AZACITIDINE (50)
HYDROXYUREA (41)
DEXAMETHASONE (38)
CYTARABINE (33)
PREDNISONE (25)
Which MITOXANTRONE Alternatives Have Lower Differentiation syndrome Risk?
MITOXANTRONE vs MITRAGYNINE\HERBALS
MITOXANTRONE vs MIZORIBINE
MITOXANTRONE vs MOBOCERTINIB
MITOXANTRONE vs MOCLOBEMIDE
MITOXANTRONE vs MODAFINIL