Does MITOXANTRONE Cause Hepatic failure? 35 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 35 reports of Hepatic failure have been filed in association with MITOXANTRONE (mitoXANTRONE). This represents 0.8% of all adverse event reports for MITOXANTRONE.
35
Reports of Hepatic failure with MITOXANTRONE
0.8%
of all MITOXANTRONE reports
15
Deaths
25
Hospitalizations
How Dangerous Is Hepatic failure From MITOXANTRONE?
Of the 35 reports, 15 (42.9%) resulted in death, 25 (71.4%) required hospitalization, and 2 (5.7%) were considered life-threatening.
Is Hepatic failure Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for MITOXANTRONE. However, 35 reports have been filed with the FAERS database.
What Other Side Effects Does MITOXANTRONE Cause?
Febrile neutropenia (668)
Off label use (368)
Neutropenia (296)
Drug ineffective (293)
Thrombocytopenia (256)
Sepsis (240)
Pyrexia (214)
Product use in unapproved indication (177)
Disease progression (173)
Acute myeloid leukaemia (167)
What Other Drugs Cause Hepatic failure?
ACETAMINOPHEN (1,392)
RIBAVIRIN (888)
CYCLOPHOSPHAMIDE (629)
METHOTREXATE (598)
BEVACIZUMAB (558)
SOFOSBUVIR (525)
RITUXIMAB (513)
VINCRISTINE (468)
DOXORUBICIN (462)
PREDNISOLONE (425)
Which MITOXANTRONE Alternatives Have Lower Hepatic failure Risk?
MITOXANTRONE vs MITRAGYNINE\HERBALS
MITOXANTRONE vs MIZORIBINE
MITOXANTRONE vs MOBOCERTINIB
MITOXANTRONE vs MOCLOBEMIDE
MITOXANTRONE vs MODAFINIL