Does NATALIZUMAB Cause Hepatic failure? 45 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 45 reports of Hepatic failure have been filed in association with NATALIZUMAB (TYRUKO). This represents 0.1% of all adverse event reports for NATALIZUMAB.
45
Reports of Hepatic failure with NATALIZUMAB
0.1%
of all NATALIZUMAB reports
7
Deaths
27
Hospitalizations
How Dangerous Is Hepatic failure From NATALIZUMAB?
Of the 45 reports, 7 (15.6%) resulted in death, 27 (60.0%) required hospitalization, and 3 (6.7%) were considered life-threatening.
Is Hepatic failure Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for NATALIZUMAB. However, 45 reports have been filed with the FAERS database.
What Other Side Effects Does NATALIZUMAB Cause?
Multiple sclerosis relapse (6,478)
Fatigue (4,456)
Multiple sclerosis (4,078)
Memory impairment (3,024)
Malaise (2,523)
Fall (2,481)
Headache (2,476)
Gait disturbance (2,427)
Prescribed underdose (2,162)
Maternal exposure during pregnancy (1,948)
What Other Drugs Cause Hepatic failure?
ACETAMINOPHEN (1,392)
RIBAVIRIN (888)
CYCLOPHOSPHAMIDE (629)
METHOTREXATE (598)
BEVACIZUMAB (558)
SOFOSBUVIR (525)
RITUXIMAB (513)
VINCRISTINE (468)
DOXORUBICIN (462)
PREDNISOLONE (425)
Which NATALIZUMAB Alternatives Have Lower Hepatic failure Risk?
NATALIZUMAB vs NATALIZUMAB-SZTN
NATALIZUMAB vs NATAMYCIN
NATALIZUMAB vs NATEGLINIDE
NATALIZUMAB vs NAVITOCLAX
NATALIZUMAB vs NAXITAMAB-GQGK