Does NATALIZUMAB Cause Osteonecrosis? 80 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 80 reports of Osteonecrosis have been filed in association with NATALIZUMAB (TYRUKO). This represents 0.1% of all adverse event reports for NATALIZUMAB.
80
Reports of Osteonecrosis with NATALIZUMAB
0.1%
of all NATALIZUMAB reports
0
Deaths
44
Hospitalizations
How Dangerous Is Osteonecrosis From NATALIZUMAB?
Of the 80 reports, 44 (55.0%) required hospitalization.
Is Osteonecrosis Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for NATALIZUMAB. However, 80 reports have been filed with the FAERS database.
What Other Side Effects Does NATALIZUMAB Cause?
Multiple sclerosis relapse (6,478)
Fatigue (4,456)
Multiple sclerosis (4,078)
Memory impairment (3,024)
Malaise (2,523)
Fall (2,481)
Headache (2,476)
Gait disturbance (2,427)
Prescribed underdose (2,162)
Maternal exposure during pregnancy (1,948)
What Other Drugs Cause Osteonecrosis?
EMTRICITABINE\TENOFOVIR DISOPROXIL (8,935)
TENOFOVIR DISOPROXIL (7,182)
EFAVIRENZ\EMTRICITABINE\TENOFOVIR DISOPROXIL (4,338)
COBICISTAT\ELVITEGRAVIR\EMTRICITABINE\TENOFOVIR DISOPROXIL (2,081)
EMTRICITABINE\RILPIVIRINE\TENOFOVIR DISOPROXIL (1,492)
PREDNISONE (779)
PREDNISOLONE (711)
DENOSUMAB (567)
METHOTREXATE (563)
DEXAMETHASONE (531)
Which NATALIZUMAB Alternatives Have Lower Osteonecrosis Risk?
NATALIZUMAB vs NATALIZUMAB-SZTN
NATALIZUMAB vs NATAMYCIN
NATALIZUMAB vs NATEGLINIDE
NATALIZUMAB vs NAVITOCLAX
NATALIZUMAB vs NAXITAMAB-GQGK