Does NIRAPARIB Cause Bone marrow failure? 76 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 76 reports of Bone marrow failure have been filed in association with NIRAPARIB (ZEJULA). This represents 0.4% of all adverse event reports for NIRAPARIB.
76
Reports of Bone marrow failure with NIRAPARIB
0.4%
of all NIRAPARIB reports
5
Deaths
38
Hospitalizations
How Dangerous Is Bone marrow failure From NIRAPARIB?
Of the 76 reports, 5 (6.6%) resulted in death, 38 (50.0%) required hospitalization, and 17 (22.4%) were considered life-threatening.
Is Bone marrow failure Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for NIRAPARIB. However, 76 reports have been filed with the FAERS database.
What Other Side Effects Does NIRAPARIB Cause?
Nausea (5,794)
Fatigue (5,240)
Constipation (4,128)
Platelet count decreased (4,102)
Insomnia (2,861)
Blood pressure increased (2,464)
Headache (2,383)
Off label use (2,213)
Vomiting (2,029)
Carbohydrate antigen 125 increased (1,868)
What Other Drugs Cause Bone marrow failure?
CYCLOPHOSPHAMIDE (1,834)
METHOTREXATE (1,401)
ETOPOSIDE (1,081)
RITUXIMAB (1,060)
CYTARABINE (1,052)
VINCRISTINE (1,001)
DOXORUBICIN (1,000)
PALBOCICLIB (951)
CARBOPLATIN (855)
BEVACIZUMAB (835)
Which NIRAPARIB Alternatives Have Lower Bone marrow failure Risk?
NIRAPARIB vs NIRMATRELVIR\RITONAVIR
NIRAPARIB vs NIROGACESTAT
NIRAPARIB vs NIROGACESTAT HYDROBROMIDE
NIRAPARIB vs NIRSEVIMAB
NIRAPARIB vs NIRSEVIMAB-ALIP