Does NIRAPARIB Cause Clostridium difficile infection? 28 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 28 reports of Clostridium difficile infection have been filed in association with NIRAPARIB (ZEJULA). This represents 0.1% of all adverse event reports for NIRAPARIB.
28
Reports of Clostridium difficile infection with NIRAPARIB
0.1%
of all NIRAPARIB reports
1
Deaths
17
Hospitalizations
How Dangerous Is Clostridium difficile infection From NIRAPARIB?
Of the 28 reports, 1 (3.6%) resulted in death, 17 (60.7%) required hospitalization.
Is Clostridium difficile infection Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for NIRAPARIB. However, 28 reports have been filed with the FAERS database.
What Other Side Effects Does NIRAPARIB Cause?
Nausea (5,794)
Fatigue (5,240)
Constipation (4,128)
Platelet count decreased (4,102)
Insomnia (2,861)
Blood pressure increased (2,464)
Headache (2,383)
Off label use (2,213)
Vomiting (2,029)
Carbohydrate antigen 125 increased (1,868)
What Other Drugs Cause Clostridium difficile infection?
ADALIMUMAB (1,502)
INFLIXIMAB (1,419)
VEDOLIZUMAB (1,130)
LENALIDOMIDE (814)
VANCOMYCIN (743)
METRONIDAZOLE (619)
PREDNISONE (618)
METHOTREXATE (588)
RITUXIMAB (532)
CIPROFLOXACIN (508)
Which NIRAPARIB Alternatives Have Lower Clostridium difficile infection Risk?
NIRAPARIB vs NIRMATRELVIR\RITONAVIR
NIRAPARIB vs NIROGACESTAT
NIRAPARIB vs NIROGACESTAT HYDROBROMIDE
NIRAPARIB vs NIRSEVIMAB
NIRAPARIB vs NIRSEVIMAB-ALIP