Does NIRAPARIB Cause Renal impairment? 670 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 670 reports of Renal impairment have been filed in association with NIRAPARIB (ZEJULA). This represents 3.1% of all adverse event reports for NIRAPARIB.
670
Reports of Renal impairment with NIRAPARIB
3.1%
of all NIRAPARIB reports
14
Deaths
99
Hospitalizations
How Dangerous Is Renal impairment From NIRAPARIB?
Of the 670 reports, 14 (2.1%) resulted in death, 99 (14.8%) required hospitalization, and 13 (1.9%) were considered life-threatening.
Is Renal impairment Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for NIRAPARIB. However, 670 reports have been filed with the FAERS database.
What Other Side Effects Does NIRAPARIB Cause?
Nausea (5,794)
Fatigue (5,240)
Constipation (4,128)
Platelet count decreased (4,102)
Insomnia (2,861)
Blood pressure increased (2,464)
Headache (2,383)
Off label use (2,213)
Vomiting (2,029)
Carbohydrate antigen 125 increased (1,868)
What Other Drugs Cause Renal impairment?
LENALIDOMIDE (2,161)
EMTRICITABINE\TENOFOVIR DISOPROXIL (2,128)
TACROLIMUS (2,124)
OMEPRAZOLE (2,075)
LANSOPRAZOLE (2,063)
METHOTREXATE (1,852)
ESOMEPRAZOLE (1,811)
PANTOPRAZOLE (1,713)
SACUBITRIL\VALSARTAN (1,610)
CYCLOSPORINE (1,489)
Which NIRAPARIB Alternatives Have Lower Renal impairment Risk?
NIRAPARIB vs NIRMATRELVIR\RITONAVIR
NIRAPARIB vs NIROGACESTAT
NIRAPARIB vs NIROGACESTAT HYDROBROMIDE
NIRAPARIB vs NIRSEVIMAB
NIRAPARIB vs NIRSEVIMAB-ALIP