Does NIVOLUMAB Cause Encephalopathy? 287 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 287 reports of Encephalopathy have been filed in association with NIVOLUMAB (OPDIVO). This represents 0.3% of all adverse event reports for NIVOLUMAB.
287
Reports of Encephalopathy with NIVOLUMAB
0.3%
of all NIVOLUMAB reports
84
Deaths
231
Hospitalizations
How Dangerous Is Encephalopathy From NIVOLUMAB?
Of the 287 reports, 84 (29.3%) resulted in death, 231 (80.5%) required hospitalization, and 53 (18.5%) were considered life-threatening.
Is Encephalopathy Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for NIVOLUMAB. However, 287 reports have been filed with the FAERS database.
What Other Side Effects Does NIVOLUMAB Cause?
Death (11,216)
Malignant neoplasm progression (9,363)
Off label use (5,208)
Diarrhoea (4,692)
Fatigue (3,709)
Pyrexia (3,454)
Intentional product use issue (3,297)
Rash (2,816)
Nausea (2,805)
Decreased appetite (2,619)
What Other Drugs Cause Encephalopathy?
BACLOFEN (845)
METHOTREXATE (775)
ACETAMINOPHEN (608)
IFOSFAMIDE (585)
CYCLOPHOSPHAMIDE (552)
TACROLIMUS (523)
PREDNISONE (489)
DEXAMETHASONE (428)
METFORMIN (418)
ETOPOSIDE (404)
Which NIVOLUMAB Alternatives Have Lower Encephalopathy Risk?
NIVOLUMAB vs NIVOLUMAB\RELATLIMAB-RMBW
NIVOLUMAB vs NIZATIDINE
NIVOLUMAB vs NOMEGESTROL
NIVOLUMAB vs NORDAZEPAM
NIVOLUMAB vs NOREPINEPHRINE