Does OLAPARIB Cause Cachexia? 10 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 10 reports of Cachexia have been filed in association with OLAPARIB (Lynparza). This represents 0.1% of all adverse event reports for OLAPARIB.
10
Reports of Cachexia with OLAPARIB
0.1%
of all OLAPARIB reports
8
Deaths
5
Hospitalizations
How Dangerous Is Cachexia From OLAPARIB?
Of the 10 reports, 8 (80.0%) resulted in death, 5 (50.0%) required hospitalization, and 2 (20.0%) were considered life-threatening.
Is Cachexia Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for OLAPARIB. However, 10 reports have been filed with the FAERS database.
What Other Side Effects Does OLAPARIB Cause?
Death (4,378)
Malignant neoplasm progression (1,862)
Nausea (1,582)
Anaemia (1,455)
Fatigue (1,437)
Off label use (777)
Vomiting (642)
Drug ineffective (563)
Diarrhoea (514)
Asthenia (491)
What Other Drugs Cause Cachexia?
NIVOLUMAB (314)
METHOTREXATE (134)
PREDNISONE (102)
CARBIDOPA\LEVODOPA (96)
PACLITAXEL (94)
FLUOROURACIL (93)
MYCOPHENOLATE MOFETIL (90)
TACROLIMUS (85)
ADALIMUMAB (84)
CYCLOPHOSPHAMIDE (83)
Which OLAPARIB Alternatives Have Lower Cachexia Risk?
OLAPARIB vs OLARATUMAB
OLAPARIB vs OLECLUMAB
OLAPARIB vs OLIVE OIL\SOYBEAN OIL
OLAPARIB vs OLMESARTAN
OLAPARIB vs OLMESARTAN MEDOXOMIL