Does OLAPARIB Cause Hepatic failure? 31 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 31 reports of Hepatic failure have been filed in association with OLAPARIB (Lynparza). This represents 0.2% of all adverse event reports for OLAPARIB.
31
Reports of Hepatic failure with OLAPARIB
0.2%
of all OLAPARIB reports
13
Deaths
9
Hospitalizations
How Dangerous Is Hepatic failure From OLAPARIB?
Of the 31 reports, 13 (41.9%) resulted in death, 9 (29.0%) required hospitalization, and 1 (3.2%) were considered life-threatening.
Is Hepatic failure Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for OLAPARIB. However, 31 reports have been filed with the FAERS database.
What Other Side Effects Does OLAPARIB Cause?
Death (4,378)
Malignant neoplasm progression (1,862)
Nausea (1,582)
Anaemia (1,455)
Fatigue (1,437)
Off label use (777)
Vomiting (642)
Drug ineffective (563)
Diarrhoea (514)
Asthenia (491)
What Other Drugs Cause Hepatic failure?
ACETAMINOPHEN (1,392)
RIBAVIRIN (888)
CYCLOPHOSPHAMIDE (629)
METHOTREXATE (598)
BEVACIZUMAB (558)
SOFOSBUVIR (525)
RITUXIMAB (513)
VINCRISTINE (468)
DOXORUBICIN (462)
PREDNISOLONE (425)
Which OLAPARIB Alternatives Have Lower Hepatic failure Risk?
OLAPARIB vs OLARATUMAB
OLAPARIB vs OLECLUMAB
OLAPARIB vs OLIVE OIL\SOYBEAN OIL
OLAPARIB vs OLMESARTAN
OLAPARIB vs OLMESARTAN MEDOXOMIL