Does PACLITAXEL Cause Hepatic failure? 348 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 348 reports of Hepatic failure have been filed in association with PACLITAXEL (PACLITAXEL PACLITAXEL). This represents 0.5% of all adverse event reports for PACLITAXEL.
348
Reports of Hepatic failure with PACLITAXEL
0.5%
of all PACLITAXEL reports
198
Deaths
168
Hospitalizations
How Dangerous Is Hepatic failure From PACLITAXEL?
Of the 348 reports, 198 (56.9%) resulted in death, 168 (48.3%) required hospitalization, and 63 (18.1%) were considered life-threatening.
Is Hepatic failure Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for PACLITAXEL. However, 348 reports have been filed with the FAERS database.
What Other Side Effects Does PACLITAXEL Cause?
Neutropenia (4,553)
Nausea (4,521)
Dyspnoea (4,519)
Diarrhoea (4,289)
Off label use (4,075)
Anaemia (3,949)
Neuropathy peripheral (3,508)
Malignant neoplasm progression (3,484)
Fatigue (3,418)
Death (3,143)
What Other Drugs Cause Hepatic failure?
ACETAMINOPHEN (1,392)
RIBAVIRIN (888)
CYCLOPHOSPHAMIDE (629)
METHOTREXATE (598)
BEVACIZUMAB (558)
SOFOSBUVIR (525)
RITUXIMAB (513)
VINCRISTINE (468)
DOXORUBICIN (462)
PREDNISOLONE (425)
Which PACLITAXEL Alternatives Have Lower Hepatic failure Risk?
PACLITAXEL vs PACRITINIB
PACLITAXEL vs PALBOCICLIB
PACLITAXEL vs PALIPERIDONE
PACLITAXEL vs PALIVIZUMAB
PACLITAXEL vs PALONOSETRON