Does PACLITAXEL Cause Hepatic necrosis? 12 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 12 reports of Hepatic necrosis have been filed in association with PACLITAXEL (PACLITAXEL PACLITAXEL). This represents 0.0% of all adverse event reports for PACLITAXEL.
12
Reports of Hepatic necrosis with PACLITAXEL
0.0%
of all PACLITAXEL reports
6
Deaths
8
Hospitalizations
How Dangerous Is Hepatic necrosis From PACLITAXEL?
Of the 12 reports, 6 (50.0%) resulted in death, 8 (66.7%) required hospitalization, and 3 (25.0%) were considered life-threatening.
Is Hepatic necrosis Listed in the Official Label?
Yes, Hepatic necrosis is listed as a known adverse reaction in the official FDA drug label for PACLITAXEL.
What Other Side Effects Does PACLITAXEL Cause?
Neutropenia (4,553)
Nausea (4,521)
Dyspnoea (4,519)
Diarrhoea (4,289)
Off label use (4,075)
Anaemia (3,949)
Neuropathy peripheral (3,508)
Malignant neoplasm progression (3,484)
Fatigue (3,418)
Death (3,143)
What Other Drugs Cause Hepatic necrosis?
ACETAMINOPHEN (216)
CYCLOPHOSPHAMIDE (83)
PREDNISONE (78)
VENLAFAXINE (69)
TACROLIMUS (67)
MYCOPHENOLATE MOFETIL (61)
METHOTREXATE (55)
METHYLPREDNISOLONE (55)
SOMATROPIN (50)
DIMETHYL SULFONE (49)
Which PACLITAXEL Alternatives Have Lower Hepatic necrosis Risk?
PACLITAXEL vs PACRITINIB
PACLITAXEL vs PALBOCICLIB
PACLITAXEL vs PALIPERIDONE
PACLITAXEL vs PALIVIZUMAB
PACLITAXEL vs PALONOSETRON