Does PACLITAXEL Cause Ototoxicity? 55 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 55 reports of Ototoxicity have been filed in association with PACLITAXEL (PACLITAXEL PACLITAXEL). This represents 0.1% of all adverse event reports for PACLITAXEL.
55
Reports of Ototoxicity with PACLITAXEL
0.1%
of all PACLITAXEL reports
4
Deaths
4
Hospitalizations
How Dangerous Is Ototoxicity From PACLITAXEL?
Of the 55 reports, 4 (7.3%) resulted in death, 4 (7.3%) required hospitalization, and 2 (3.6%) were considered life-threatening.
Is Ototoxicity Listed in the Official Label?
Yes, Ototoxicity is listed as a known adverse reaction in the official FDA drug label for PACLITAXEL.
What Other Side Effects Does PACLITAXEL Cause?
Neutropenia (4,553)
Nausea (4,521)
Dyspnoea (4,519)
Diarrhoea (4,289)
Off label use (4,075)
Anaemia (3,949)
Neuropathy peripheral (3,508)
Malignant neoplasm progression (3,484)
Fatigue (3,418)
Death (3,143)
What Other Drugs Cause Ototoxicity?
CISPLATIN (273)
CARBOPLATIN (208)
VINCRISTINE (194)
AMIKACIN (158)
ETOPOSIDE (121)
GENTAMICIN (108)
CYCLOSPORINE (105)
VANCOMYCIN (87)
LINEZOLID (82)
TOBRAMYCIN (78)
Which PACLITAXEL Alternatives Have Lower Ototoxicity Risk?
PACLITAXEL vs PACRITINIB
PACLITAXEL vs PALBOCICLIB
PACLITAXEL vs PALIPERIDONE
PACLITAXEL vs PALIVIZUMAB
PACLITAXEL vs PALONOSETRON