Does PAMIDRONATE Cause Osteonecrosis? 41 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 41 reports of Osteonecrosis have been filed in association with PAMIDRONATE (Pamidronate Disodium). This represents 2.5% of all adverse event reports for PAMIDRONATE.
41
Reports of Osteonecrosis with PAMIDRONATE
2.5%
of all PAMIDRONATE reports
2
Deaths
5
Hospitalizations
How Dangerous Is Osteonecrosis From PAMIDRONATE?
Of the 41 reports, 2 (4.9%) resulted in death, 5 (12.2%) required hospitalization, and 3 (7.3%) were considered life-threatening.
Is Osteonecrosis Listed in the Official Label?
Yes, Osteonecrosis is listed as a known adverse reaction in the official FDA drug label for PAMIDRONATE.
What Other Side Effects Does PAMIDRONATE Cause?
Osteonecrosis of jaw (313)
Drug ineffective (180)
Pain (164)
Off label use (143)
Pyrexia (106)
Malignant neoplasm progression (103)
Dyspnoea (102)
Fatigue (97)
Pain in jaw (97)
Metastases to bone (95)
What Other Drugs Cause Osteonecrosis?
EMTRICITABINE\TENOFOVIR DISOPROXIL (8,935)
TENOFOVIR DISOPROXIL (7,182)
EFAVIRENZ\EMTRICITABINE\TENOFOVIR DISOPROXIL (4,338)
COBICISTAT\ELVITEGRAVIR\EMTRICITABINE\TENOFOVIR DISOPROXIL (2,081)
EMTRICITABINE\RILPIVIRINE\TENOFOVIR DISOPROXIL (1,492)
PREDNISONE (779)
PREDNISOLONE (711)
DENOSUMAB (567)
METHOTREXATE (563)
DEXAMETHASONE (531)
Which PAMIDRONATE Alternatives Have Lower Osteonecrosis Risk?
PAMIDRONATE vs PAMIDRONIC ACID
PAMIDRONATE vs PANCRELIPASE
PAMIDRONATE vs PANCRELIPASE AMYLASE\PANCRELIPASE LIPASE\PANCRELIPASE PROTEASE
PAMIDRONATE vs PANCURONIUM
PAMIDRONATE vs PANITUMUMAB