Does PEMBROLIZUMAB Cause Depression? 185 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 185 reports of Depression have been filed in association with PEMBROLIZUMAB (KEYTRUDA). This represents 0.2% of all adverse event reports for PEMBROLIZUMAB.
185
Reports of Depression with PEMBROLIZUMAB
0.2%
of all PEMBROLIZUMAB reports
32
Deaths
68
Hospitalizations
How Dangerous Is Depression From PEMBROLIZUMAB?
Of the 185 reports, 32 (17.3%) resulted in death, 68 (36.8%) required hospitalization, and 8 (4.3%) were considered life-threatening.
Is Depression Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for PEMBROLIZUMAB. However, 185 reports have been filed with the FAERS database.
What Other Side Effects Does PEMBROLIZUMAB Cause?
Malignant neoplasm progression (10,111)
Death (4,744)
Diarrhoea (4,251)
Fatigue (3,833)
Off label use (3,416)
Product use in unapproved indication (3,191)
Pyrexia (3,155)
Rash (2,900)
Nausea (2,670)
Decreased appetite (2,486)
What Other Drugs Cause Depression?
OXYCODONE (6,871)
ADALIMUMAB (6,340)
APREMILAST (5,129)
ACETAMINOPHEN\OXYCODONE (4,035)
ACETAMINOPHEN\HYDROCODONE (3,699)
METHOTREXATE (3,577)
ETANERCEPT (3,538)
LEVONORGESTREL (3,529)
MORPHINE (3,280)
PREDNISONE (3,211)
Which PEMBROLIZUMAB Alternatives Have Lower Depression Risk?
PEMBROLIZUMAB vs PEMETREXED
PEMBROLIZUMAB vs PEMIGATINIB
PEMBROLIZUMAB vs PENICILLAMINE
PEMBROLIZUMAB vs PENICILLIN
PEMBROLIZUMAB vs PENICILLIN G