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Important: This site presents data from the FDA Adverse Event Reporting System (FAERS). A report does not mean the drug caused the event. Full disclaimer.

Does PEMBROLIZUMAB Cause Hepatic failure? 277 Reports in FDA Database

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According to the FDA Adverse Event Reporting System (FAERS), 277 reports of Hepatic failure have been filed in association with PEMBROLIZUMAB (KEYTRUDA). This represents 0.3% of all adverse event reports for PEMBROLIZUMAB.

277
Reports of Hepatic failure with PEMBROLIZUMAB
0.3%
of all PEMBROLIZUMAB reports
148
Deaths
167
Hospitalizations

How Dangerous Is Hepatic failure From PEMBROLIZUMAB?

Of the 277 reports, 148 (53.4%) resulted in death, 167 (60.3%) required hospitalization, and 50 (18.1%) were considered life-threatening.

Is Hepatic failure Listed in the Official Label?

Yes, Hepatic failure is listed as a known adverse reaction in the official FDA drug label for PEMBROLIZUMAB.

What Other Side Effects Does PEMBROLIZUMAB Cause?

Malignant neoplasm progression (10,111) Death (4,744) Diarrhoea (4,251) Fatigue (3,833) Off label use (3,416) Product use in unapproved indication (3,191) Pyrexia (3,155) Rash (2,900) Nausea (2,670) Decreased appetite (2,486)

What Other Drugs Cause Hepatic failure?

ACETAMINOPHEN (1,392) RIBAVIRIN (888) CYCLOPHOSPHAMIDE (629) METHOTREXATE (598) BEVACIZUMAB (558) SOFOSBUVIR (525) RITUXIMAB (513) VINCRISTINE (468) DOXORUBICIN (462) PREDNISOLONE (425)

Which PEMBROLIZUMAB Alternatives Have Lower Hepatic failure Risk?

PEMBROLIZUMAB vs PEMETREXED PEMBROLIZUMAB vs PEMIGATINIB PEMBROLIZUMAB vs PENICILLAMINE PEMBROLIZUMAB vs PENICILLIN PEMBROLIZUMAB vs PENICILLIN G

Related Pages

PEMBROLIZUMAB Full Profile All Hepatic failure Reports All Drugs Causing Hepatic failure PEMBROLIZUMAB Demographics