Does PEMBROLIZUMAB Cause Hypercalcaemia? 128 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 128 reports of Hypercalcaemia have been filed in association with PEMBROLIZUMAB (KEYTRUDA). This represents 0.2% of all adverse event reports for PEMBROLIZUMAB.
128
Reports of Hypercalcaemia with PEMBROLIZUMAB
0.2%
of all PEMBROLIZUMAB reports
34
Deaths
78
Hospitalizations
How Dangerous Is Hypercalcaemia From PEMBROLIZUMAB?
Of the 128 reports, 34 (26.6%) resulted in death, 78 (60.9%) required hospitalization, and 18 (14.1%) were considered life-threatening.
Is Hypercalcaemia Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for PEMBROLIZUMAB. However, 128 reports have been filed with the FAERS database.
What Other Side Effects Does PEMBROLIZUMAB Cause?
Malignant neoplasm progression (10,111)
Death (4,744)
Diarrhoea (4,251)
Fatigue (3,833)
Off label use (3,416)
Product use in unapproved indication (3,191)
Pyrexia (3,155)
Rash (2,900)
Nausea (2,670)
Decreased appetite (2,486)
What Other Drugs Cause Hypercalcaemia?
RITUXIMAB (857)
METHOTREXATE (803)
ADALIMUMAB (663)
TOCILIZUMAB (618)
ABATACEPT (612)
ETANERCEPT (602)
DENOSUMAB (599)
ALENDRONATE (594)
INFLIXIMAB (594)
LEFLUNOMIDE (585)
Which PEMBROLIZUMAB Alternatives Have Lower Hypercalcaemia Risk?
PEMBROLIZUMAB vs PEMETREXED
PEMBROLIZUMAB vs PEMIGATINIB
PEMBROLIZUMAB vs PENICILLAMINE
PEMBROLIZUMAB vs PENICILLIN
PEMBROLIZUMAB vs PENICILLIN G