Does PEMBROLIZUMAB Cause Polyneuropathy? 125 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 125 reports of Polyneuropathy have been filed in association with PEMBROLIZUMAB (KEYTRUDA). This represents 0.2% of all adverse event reports for PEMBROLIZUMAB.
125
Reports of Polyneuropathy with PEMBROLIZUMAB
0.2%
of all PEMBROLIZUMAB reports
12
Deaths
53
Hospitalizations
How Dangerous Is Polyneuropathy From PEMBROLIZUMAB?
Of the 125 reports, 12 (9.6%) resulted in death, 53 (42.4%) required hospitalization, and 11 (8.8%) were considered life-threatening.
Is Polyneuropathy Listed in the Official Label?
Yes, Polyneuropathy is listed as a known adverse reaction in the official FDA drug label for PEMBROLIZUMAB.
What Other Side Effects Does PEMBROLIZUMAB Cause?
Malignant neoplasm progression (10,111)
Death (4,744)
Diarrhoea (4,251)
Fatigue (3,833)
Off label use (3,416)
Product use in unapproved indication (3,191)
Pyrexia (3,155)
Rash (2,900)
Nausea (2,670)
Decreased appetite (2,486)
What Other Drugs Cause Polyneuropathy?
DEXAMETHASONE (953)
BORTEZOMIB (890)
PACLITAXEL (741)
OXALIPLATIN (691)
CYCLOPHOSPHAMIDE (686)
FLUOROURACIL (525)
TRASTUZUMAB (478)
CARBOPLATIN (463)
DOXORUBICIN (452)
VINCRISTINE (440)
Which PEMBROLIZUMAB Alternatives Have Lower Polyneuropathy Risk?
PEMBROLIZUMAB vs PEMETREXED
PEMBROLIZUMAB vs PEMIGATINIB
PEMBROLIZUMAB vs PENICILLAMINE
PEMBROLIZUMAB vs PENICILLIN
PEMBROLIZUMAB vs PENICILLIN G