Does PEMETREXED Cause Bone marrow failure? 271 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 271 reports of Bone marrow failure have been filed in association with PEMETREXED (Pemetrexed). This represents 1.2% of all adverse event reports for PEMETREXED.
271
Reports of Bone marrow failure with PEMETREXED
1.2%
of all PEMETREXED reports
86
Deaths
137
Hospitalizations
How Dangerous Is Bone marrow failure From PEMETREXED?
Of the 271 reports, 86 (31.7%) resulted in death, 137 (50.6%) required hospitalization, and 33 (12.2%) were considered life-threatening.
Is Bone marrow failure Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for PEMETREXED. However, 271 reports have been filed with the FAERS database.
What Other Side Effects Does PEMETREXED Cause?
Malignant neoplasm progression (2,149)
Off label use (1,663)
Anaemia (1,430)
Pancytopenia (1,236)
Neutropenia (1,200)
Nausea (1,195)
Diarrhoea (1,165)
Acute kidney injury (1,105)
Thrombocytopenia (1,059)
Disease progression (969)
What Other Drugs Cause Bone marrow failure?
CYCLOPHOSPHAMIDE (1,834)
METHOTREXATE (1,401)
ETOPOSIDE (1,081)
RITUXIMAB (1,060)
CYTARABINE (1,052)
VINCRISTINE (1,001)
DOXORUBICIN (1,000)
PALBOCICLIB (951)
CARBOPLATIN (855)
BEVACIZUMAB (835)
Which PEMETREXED Alternatives Have Lower Bone marrow failure Risk?
PEMETREXED vs PEMIGATINIB
PEMETREXED vs PENICILLAMINE
PEMETREXED vs PENICILLIN
PEMETREXED vs PENICILLIN G
PEMETREXED vs PENICILLIN G BENZATHINE