Does PEMETREXED Cause Haematotoxicity? 230 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 230 reports of Haematotoxicity have been filed in association with PEMETREXED (Pemetrexed). This represents 1.0% of all adverse event reports for PEMETREXED.
230
Reports of Haematotoxicity with PEMETREXED
1.0%
of all PEMETREXED reports
77
Deaths
55
Hospitalizations
How Dangerous Is Haematotoxicity From PEMETREXED?
Of the 230 reports, 77 (33.5%) resulted in death, 55 (23.9%) required hospitalization, and 16 (7.0%) were considered life-threatening.
Is Haematotoxicity Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for PEMETREXED. However, 230 reports have been filed with the FAERS database.
What Other Side Effects Does PEMETREXED Cause?
Malignant neoplasm progression (2,149)
Off label use (1,663)
Anaemia (1,430)
Pancytopenia (1,236)
Neutropenia (1,200)
Nausea (1,195)
Diarrhoea (1,165)
Acute kidney injury (1,105)
Thrombocytopenia (1,059)
Disease progression (969)
What Other Drugs Cause Haematotoxicity?
CYCLOPHOSPHAMIDE (1,410)
DOXORUBICIN (1,180)
VINCRISTINE (1,038)
RITUXIMAB (812)
CARBOPLATIN (803)
METHOTREXATE (799)
PREDNISONE (730)
CYTARABINE (701)
ETOPOSIDE (677)
CISPLATIN (668)
Which PEMETREXED Alternatives Have Lower Haematotoxicity Risk?
PEMETREXED vs PEMIGATINIB
PEMETREXED vs PENICILLAMINE
PEMETREXED vs PENICILLIN
PEMETREXED vs PENICILLIN G
PEMETREXED vs PENICILLIN G BENZATHINE