Does PEMETREXED Cause Hepatocellular injury? 170 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 170 reports of Hepatocellular injury have been filed in association with PEMETREXED (Pemetrexed). This represents 0.7% of all adverse event reports for PEMETREXED.
170
Reports of Hepatocellular injury with PEMETREXED
0.7%
of all PEMETREXED reports
12
Deaths
90
Hospitalizations
How Dangerous Is Hepatocellular injury From PEMETREXED?
Of the 170 reports, 12 (7.1%) resulted in death, 90 (52.9%) required hospitalization, and 5 (2.9%) were considered life-threatening.
Is Hepatocellular injury Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for PEMETREXED. However, 170 reports have been filed with the FAERS database.
What Other Side Effects Does PEMETREXED Cause?
Malignant neoplasm progression (2,149)
Off label use (1,663)
Anaemia (1,430)
Pancytopenia (1,236)
Neutropenia (1,200)
Nausea (1,195)
Diarrhoea (1,165)
Acute kidney injury (1,105)
Thrombocytopenia (1,059)
Disease progression (969)
What Other Drugs Cause Hepatocellular injury?
ACETAMINOPHEN (1,761)
METHOTREXATE (683)
ATORVASTATIN (610)
SULFAMETHOXAZOLE\TRIMETHOPRIM (415)
ENOXAPARIN (365)
TRAMADOL (349)
AMOXICILLIN (347)
ESOMEPRAZOLE (341)
PANTOPRAZOLE (340)
VINCRISTINE (306)
Which PEMETREXED Alternatives Have Lower Hepatocellular injury Risk?
PEMETREXED vs PEMIGATINIB
PEMETREXED vs PENICILLAMINE
PEMETREXED vs PENICILLIN
PEMETREXED vs PENICILLIN G
PEMETREXED vs PENICILLIN G BENZATHINE