Does PEMETREXED Cause Hypothyroidism? 256 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 256 reports of Hypothyroidism have been filed in association with PEMETREXED (Pemetrexed). This represents 1.1% of all adverse event reports for PEMETREXED.
256
Reports of Hypothyroidism with PEMETREXED
1.1%
of all PEMETREXED reports
8
Deaths
71
Hospitalizations
How Dangerous Is Hypothyroidism From PEMETREXED?
Of the 256 reports, 8 (3.1%) resulted in death, 71 (27.7%) required hospitalization, and 7 (2.7%) were considered life-threatening.
Is Hypothyroidism Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for PEMETREXED. However, 256 reports have been filed with the FAERS database.
What Other Side Effects Does PEMETREXED Cause?
Malignant neoplasm progression (2,149)
Off label use (1,663)
Anaemia (1,430)
Pancytopenia (1,236)
Neutropenia (1,200)
Nausea (1,195)
Diarrhoea (1,165)
Acute kidney injury (1,105)
Thrombocytopenia (1,059)
Disease progression (969)
What Other Drugs Cause Hypothyroidism?
PEMBROLIZUMAB (2,326)
LEVOTHYROXINE (2,107)
NIVOLUMAB (1,939)
LENVATINIB (1,375)
ATEZOLIZUMAB (881)
ALBUTEROL (877)
CARBOPLATIN (830)
IPILIMUMAB (770)
AMIODARONE (764)
PREDNISONE (739)
Which PEMETREXED Alternatives Have Lower Hypothyroidism Risk?
PEMETREXED vs PEMIGATINIB
PEMETREXED vs PENICILLAMINE
PEMETREXED vs PENICILLIN
PEMETREXED vs PENICILLIN G
PEMETREXED vs PENICILLIN G BENZATHINE