Does PEMETREXED Cause Pathological fracture? 14 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 14 reports of Pathological fracture have been filed in association with PEMETREXED (Pemetrexed). This represents 0.1% of all adverse event reports for PEMETREXED.
14
Reports of Pathological fracture with PEMETREXED
0.1%
of all PEMETREXED reports
6
Deaths
11
Hospitalizations
How Dangerous Is Pathological fracture From PEMETREXED?
Of the 14 reports, 6 (42.9%) resulted in death, 11 (78.6%) required hospitalization, and 1 (7.1%) were considered life-threatening.
Is Pathological fracture Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for PEMETREXED. However, 14 reports have been filed with the FAERS database.
What Other Side Effects Does PEMETREXED Cause?
Malignant neoplasm progression (2,149)
Off label use (1,663)
Anaemia (1,430)
Pancytopenia (1,236)
Neutropenia (1,200)
Nausea (1,195)
Diarrhoea (1,165)
Acute kidney injury (1,105)
Thrombocytopenia (1,059)
Disease progression (969)
What Other Drugs Cause Pathological fracture?
DENOSUMAB (634)
LENALIDOMIDE (260)
DEXAMETHASONE (201)
ALENDRONATE (200)
ZOLEDRONIC ACID (185)
RISEDRONATE (110)
ADALIMUMAB (93)
LETROZOLE (87)
RITUXIMAB (87)
CYCLOPHOSPHAMIDE (85)
Which PEMETREXED Alternatives Have Lower Pathological fracture Risk?
PEMETREXED vs PEMIGATINIB
PEMETREXED vs PENICILLAMINE
PEMETREXED vs PENICILLIN
PEMETREXED vs PENICILLIN G
PEMETREXED vs PENICILLIN G BENZATHINE