Does PEMETREXED Cause Thrombotic microangiopathy? 22 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 22 reports of Thrombotic microangiopathy have been filed in association with PEMETREXED (Pemetrexed). This represents 0.1% of all adverse event reports for PEMETREXED.
22
Reports of Thrombotic microangiopathy with PEMETREXED
0.1%
of all PEMETREXED reports
2
Deaths
6
Hospitalizations
How Dangerous Is Thrombotic microangiopathy From PEMETREXED?
Of the 22 reports, 2 (9.1%) resulted in death, 6 (27.3%) required hospitalization, and 4 (18.2%) were considered life-threatening.
Is Thrombotic microangiopathy Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for PEMETREXED. However, 22 reports have been filed with the FAERS database.
What Other Side Effects Does PEMETREXED Cause?
Malignant neoplasm progression (2,149)
Off label use (1,663)
Anaemia (1,430)
Pancytopenia (1,236)
Neutropenia (1,200)
Nausea (1,195)
Diarrhoea (1,165)
Acute kidney injury (1,105)
Thrombocytopenia (1,059)
Disease progression (969)
What Other Drugs Cause Thrombotic microangiopathy?
TACROLIMUS (1,982)
MYCOPHENOLATE MOFETIL (820)
CYCLOSPORINE (724)
GEMCITABINE (648)
ECULIZUMAB (636)
CYCLOPHOSPHAMIDE (602)
FLUDARABINE (480)
METHOTREXATE (447)
CARFILZOMIB (350)
METHYLPREDNISOLONE (345)
Which PEMETREXED Alternatives Have Lower Thrombotic microangiopathy Risk?
PEMETREXED vs PEMIGATINIB
PEMETREXED vs PENICILLAMINE
PEMETREXED vs PENICILLIN
PEMETREXED vs PENICILLIN G
PEMETREXED vs PENICILLIN G BENZATHINE