Does PERTUZUMAB Cause Hepatic failure? 68 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 68 reports of Hepatic failure have been filed in association with PERTUZUMAB (PERJETA). This represents 0.3% of all adverse event reports for PERTUZUMAB.
68
Reports of Hepatic failure with PERTUZUMAB
0.3%
of all PERTUZUMAB reports
31
Deaths
33
Hospitalizations
How Dangerous Is Hepatic failure From PERTUZUMAB?
Of the 68 reports, 31 (45.6%) resulted in death, 33 (48.5%) required hospitalization, and 10 (14.7%) were considered life-threatening.
Is Hepatic failure Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for PERTUZUMAB. However, 68 reports have been filed with the FAERS database.
What Other Side Effects Does PERTUZUMAB Cause?
Diarrhoea (3,343)
Off label use (1,886)
Fatigue (1,672)
Nausea (1,669)
Myelosuppression (1,311)
Disease progression (1,142)
Vomiting (1,096)
Dyspnoea (987)
Neuropathy peripheral (983)
Pyrexia (926)
What Other Drugs Cause Hepatic failure?
ACETAMINOPHEN (1,392)
RIBAVIRIN (888)
CYCLOPHOSPHAMIDE (629)
METHOTREXATE (598)
BEVACIZUMAB (558)
SOFOSBUVIR (525)
RITUXIMAB (513)
VINCRISTINE (468)
DOXORUBICIN (462)
PREDNISOLONE (425)
Which PERTUZUMAB Alternatives Have Lower Hepatic failure Risk?
PERTUZUMAB vs PERTUZUMAB\TRASTUZUMAB
PERTUZUMAB vs PETROLATUM
PERTUZUMAB vs PEVONEDISTAT
PERTUZUMAB vs PEXIDARTINIB
PERTUZUMAB vs PHENACETIN