Does PERTUZUMAB Cause Polyneuropathy? 374 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 374 reports of Polyneuropathy have been filed in association with PERTUZUMAB (PERJETA). This represents 1.7% of all adverse event reports for PERTUZUMAB.
374
Reports of Polyneuropathy with PERTUZUMAB
1.7%
of all PERTUZUMAB reports
7
Deaths
120
Hospitalizations
How Dangerous Is Polyneuropathy From PERTUZUMAB?
Of the 374 reports, 7 (1.9%) resulted in death, 120 (32.1%) required hospitalization, and 2 (0.5%) were considered life-threatening.
Is Polyneuropathy Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for PERTUZUMAB. However, 374 reports have been filed with the FAERS database.
What Other Side Effects Does PERTUZUMAB Cause?
Diarrhoea (3,343)
Off label use (1,886)
Fatigue (1,672)
Nausea (1,669)
Myelosuppression (1,311)
Disease progression (1,142)
Vomiting (1,096)
Dyspnoea (987)
Neuropathy peripheral (983)
Pyrexia (926)
What Other Drugs Cause Polyneuropathy?
DEXAMETHASONE (953)
BORTEZOMIB (890)
PACLITAXEL (741)
OXALIPLATIN (691)
CYCLOPHOSPHAMIDE (686)
FLUOROURACIL (525)
TRASTUZUMAB (478)
CARBOPLATIN (463)
DOXORUBICIN (452)
VINCRISTINE (440)
Which PERTUZUMAB Alternatives Have Lower Polyneuropathy Risk?
PERTUZUMAB vs PERTUZUMAB\TRASTUZUMAB
PERTUZUMAB vs PETROLATUM
PERTUZUMAB vs PEVONEDISTAT
PERTUZUMAB vs PEXIDARTINIB
PERTUZUMAB vs PHENACETIN