Does PHENOBARBITAL Cause Hepatic failure? 21 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 21 reports of Hepatic failure have been filed in association with PHENOBARBITAL (Phenobarbital Sodium). This represents 0.3% of all adverse event reports for PHENOBARBITAL.
21
Reports of Hepatic failure with PHENOBARBITAL
0.3%
of all PHENOBARBITAL reports
14
Deaths
7
Hospitalizations
How Dangerous Is Hepatic failure From PHENOBARBITAL?
Of the 21 reports, 14 (66.7%) resulted in death, 7 (33.3%) required hospitalization, and 1 (4.8%) were considered life-threatening.
Is Hepatic failure Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for PHENOBARBITAL. However, 21 reports have been filed with the FAERS database.
What Other Side Effects Does PHENOBARBITAL Cause?
Drug ineffective (1,686)
Off label use (781)
Seizure (620)
Multiple-drug resistance (406)
Toxicity to various agents (392)
Status epilepticus (317)
Drug reaction with eosinophilia and systemic symptoms (274)
Foetal exposure during pregnancy (266)
Hypotension (256)
Epilepsy (253)
What Other Drugs Cause Hepatic failure?
ACETAMINOPHEN (1,392)
RIBAVIRIN (888)
CYCLOPHOSPHAMIDE (629)
METHOTREXATE (598)
BEVACIZUMAB (558)
SOFOSBUVIR (525)
RITUXIMAB (513)
VINCRISTINE (468)
DOXORUBICIN (462)
PREDNISOLONE (425)
Which PHENOBARBITAL Alternatives Have Lower Hepatic failure Risk?
PHENOBARBITAL vs PHENOLPHTHALEIN
PHENOBARBITAL vs PHENOTHIAZINE
PHENOBARBITAL vs PHENPROCOUMON
PHENOBARBITAL vs PHENTERMINE
PHENOBARBITAL vs PHENTERMINE\TOPIRAMATE