Does PHENYTOIN Cause Hepatic failure? 40 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 40 reports of Hepatic failure have been filed in association with PHENYTOIN (PHENYTOIN SODIUM). This represents 0.3% of all adverse event reports for PHENYTOIN.
40
Reports of Hepatic failure with PHENYTOIN
0.3%
of all PHENYTOIN reports
11
Deaths
25
Hospitalizations
How Dangerous Is Hepatic failure From PHENYTOIN?
Of the 40 reports, 11 (27.5%) resulted in death, 25 (62.5%) required hospitalization, and 2 (5.0%) were considered life-threatening.
Is Hepatic failure Listed in the Official Label?
Yes, Hepatic failure is listed as a known adverse reaction in the official FDA drug label for PHENYTOIN.
What Other Side Effects Does PHENYTOIN Cause?
Drug ineffective (2,753)
Seizure (1,907)
Toxicity to various agents (1,248)
Drug hypersensitivity (898)
Off label use (852)
Drug interaction (772)
Drug reaction with eosinophilia and systemic symptoms (673)
Status epilepticus (544)
Fall (436)
Rash (414)
What Other Drugs Cause Hepatic failure?
ACETAMINOPHEN (1,392)
RIBAVIRIN (888)
CYCLOPHOSPHAMIDE (629)
METHOTREXATE (598)
BEVACIZUMAB (558)
SOFOSBUVIR (525)
RITUXIMAB (513)
VINCRISTINE (468)
DOXORUBICIN (462)
PREDNISOLONE (425)
Which PHENYTOIN Alternatives Have Lower Hepatic failure Risk?
PHENYTOIN vs PHLEUM PRATENSE POLLEN
PHENYTOIN vs PHLOROGLUCINOL
PHENYTOIN vs PHLOROGLUCINOL\1,3,5-TRIMETHOXYBENZENE
PHENYTOIN vs PHOLCODINE
PHENYTOIN vs PHOSPHORUS