Does PHENYTOIN Cause Hyperammonaemic encephalopathy? 40 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 40 reports of Hyperammonaemic encephalopathy have been filed in association with PHENYTOIN (PHENYTOIN SODIUM). This represents 0.3% of all adverse event reports for PHENYTOIN.
40
Reports of Hyperammonaemic encephalopathy with PHENYTOIN
0.3%
of all PHENYTOIN reports
3
Deaths
28
Hospitalizations
How Dangerous Is Hyperammonaemic encephalopathy From PHENYTOIN?
Of the 40 reports, 3 (7.5%) resulted in death, 28 (70.0%) required hospitalization, and 3 (7.5%) were considered life-threatening.
Is Hyperammonaemic encephalopathy Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for PHENYTOIN. However, 40 reports have been filed with the FAERS database.
What Other Side Effects Does PHENYTOIN Cause?
Drug ineffective (2,753)
Seizure (1,907)
Toxicity to various agents (1,248)
Drug hypersensitivity (898)
Off label use (852)
Drug interaction (772)
Drug reaction with eosinophilia and systemic symptoms (673)
Status epilepticus (544)
Fall (436)
Rash (414)
What Other Drugs Cause Hyperammonaemic encephalopathy?
VALPROIC ACID (455)
FLUOROURACIL (156)
VALPROATE (120)
DIVALPROEX (119)
OXALIPLATIN (107)
TOPIRAMATE (101)
RISPERIDONE (96)
QUETIAPINE (91)
LEVETIRACETAM (71)
LEUCOVORIN (62)
Which PHENYTOIN Alternatives Have Lower Hyperammonaemic encephalopathy Risk?
PHENYTOIN vs PHLEUM PRATENSE POLLEN
PHENYTOIN vs PHLOROGLUCINOL
PHENYTOIN vs PHLOROGLUCINOL\1,3,5-TRIMETHOXYBENZENE
PHENYTOIN vs PHOLCODINE
PHENYTOIN vs PHOSPHORUS