Does PHENYTOIN Cause Spina bifida? 31 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 31 reports of Spina bifida have been filed in association with PHENYTOIN (PHENYTOIN SODIUM). This represents 0.2% of all adverse event reports for PHENYTOIN.
31
Reports of Spina bifida with PHENYTOIN
0.2%
of all PHENYTOIN reports
3
Deaths
1
Hospitalizations
How Dangerous Is Spina bifida From PHENYTOIN?
Of the 31 reports, 3 (9.7%) resulted in death, 1 (3.2%) required hospitalization.
Is Spina bifida Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for PHENYTOIN. However, 31 reports have been filed with the FAERS database.
What Other Side Effects Does PHENYTOIN Cause?
Drug ineffective (2,753)
Seizure (1,907)
Toxicity to various agents (1,248)
Drug hypersensitivity (898)
Off label use (852)
Drug interaction (772)
Drug reaction with eosinophilia and systemic symptoms (673)
Status epilepticus (544)
Fall (436)
Rash (414)
What Other Drugs Cause Spina bifida?
OXYCODONE (268)
ACETAMINOPHEN\OXYCODONE (200)
ACETAMINOPHEN\HYDROCODONE (188)
HYDROMORPHONE (174)
MORPHINE (159)
LAMOTRIGINE (142)
TRAMADOL (136)
BUPRENORPHINE (107)
VALPROIC ACID (101)
HYDROCODONE (93)
Which PHENYTOIN Alternatives Have Lower Spina bifida Risk?
PHENYTOIN vs PHLEUM PRATENSE POLLEN
PHENYTOIN vs PHLOROGLUCINOL
PHENYTOIN vs PHLOROGLUCINOL\1,3,5-TRIMETHOXYBENZENE
PHENYTOIN vs PHOLCODINE
PHENYTOIN vs PHOSPHORUS