Does PIPERACILLIN Cause Toxic epidermal necrolysis? 45 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 45 reports of Toxic epidermal necrolysis have been filed in association with PIPERACILLIN (Piperacillin and Tazobactam). This represents 4.4% of all adverse event reports for PIPERACILLIN.
45
Reports of Toxic epidermal necrolysis with PIPERACILLIN
4.4%
of all PIPERACILLIN reports
35
Deaths
30
Hospitalizations
How Dangerous Is Toxic epidermal necrolysis From PIPERACILLIN?
Of the 45 reports, 35 (77.8%) resulted in death, 30 (66.7%) required hospitalization, and 13 (28.9%) were considered life-threatening.
Is Toxic epidermal necrolysis Listed in the Official Label?
Yes, Toxic epidermal necrolysis is listed as a known adverse reaction in the official FDA drug label for PIPERACILLIN.
What Other Side Effects Does PIPERACILLIN Cause?
Pyrexia (83)
Drug reaction with eosinophilia and systemic symptoms (77)
Drug ineffective (73)
Off label use (68)
Eosinophilia (60)
Acute kidney injury (56)
Rash (55)
Rash maculo-papular (52)
Dyspnoea (43)
Agranulocytosis (41)
What Other Drugs Cause Toxic epidermal necrolysis?
ACETAMINOPHEN (980)
LAMOTRIGINE (941)
ALLOPURINOL (858)
IBUPROFEN (764)
SULFAMETHOXAZOLE\TRIMETHOPRIM (592)
CIPROFLOXACIN (576)
FUROSEMIDE (521)
VANCOMYCIN (515)
PIPERACILLIN\TAZOBACTAM (490)
PEMBROLIZUMAB (444)
Which PIPERACILLIN Alternatives Have Lower Toxic epidermal necrolysis Risk?
PIPERACILLIN vs PIPERACILLIN\TAZOBACTAM
PIPERACILLIN vs PIRACETAM
PIPERACILLIN vs PIRARUBICIN
PIPERACILLIN vs PIRFENIDONE
PIPERACILLIN vs PIRIBEDIL