Does PIPERACILLIN Cause Agranulocytosis? 41 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 41 reports of Agranulocytosis have been filed in association with PIPERACILLIN (Piperacillin and Tazobactam). This represents 4.0% of all adverse event reports for PIPERACILLIN.
41
Reports of Agranulocytosis with PIPERACILLIN
4.0%
of all PIPERACILLIN reports
6
Deaths
23
Hospitalizations
How Dangerous Is Agranulocytosis From PIPERACILLIN?
Of the 41 reports, 6 (14.6%) resulted in death, 23 (56.1%) required hospitalization, and 17 (41.5%) were considered life-threatening.
Is Agranulocytosis Listed in the Official Label?
Yes, Agranulocytosis is listed as a known adverse reaction in the official FDA drug label for PIPERACILLIN.
What Other Side Effects Does PIPERACILLIN Cause?
Pyrexia (83)
Drug reaction with eosinophilia and systemic symptoms (77)
Drug ineffective (73)
Off label use (68)
Eosinophilia (60)
Acute kidney injury (56)
Rash (55)
Rash maculo-papular (52)
Toxic epidermal necrolysis (45)
Dyspnoea (43)
What Other Drugs Cause Agranulocytosis?
CLOZAPINE (1,766)
CYCLOPHOSPHAMIDE (1,242)
RITUXIMAB (1,154)
SULFAMETHOXAZOLE\TRIMETHOPRIM (797)
PANTOPRAZOLE (599)
METHOTREXATE (550)
SODIUM (549)
EPIRUBICIN (491)
METAMIZOLE (438)
DOCETAXEL (436)
Which PIPERACILLIN Alternatives Have Lower Agranulocytosis Risk?
PIPERACILLIN vs PIPERACILLIN\TAZOBACTAM
PIPERACILLIN vs PIRACETAM
PIPERACILLIN vs PIRARUBICIN
PIPERACILLIN vs PIRFENIDONE
PIPERACILLIN vs PIRIBEDIL