Does PIRFENIDONE Cause Hepatic failure? 18 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 18 reports of Hepatic failure have been filed in association with PIRFENIDONE (PIRFENIDONE). This represents 0.1% of all adverse event reports for PIRFENIDONE.
18
Reports of Hepatic failure with PIRFENIDONE
0.1%
of all PIRFENIDONE reports
7
Deaths
8
Hospitalizations
How Dangerous Is Hepatic failure From PIRFENIDONE?
Of the 18 reports, 7 (38.9%) resulted in death, 8 (44.4%) required hospitalization, and 1 (5.6%) were considered life-threatening.
Is Hepatic failure Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for PIRFENIDONE. However, 18 reports have been filed with the FAERS database.
What Other Side Effects Does PIRFENIDONE Cause?
Death (7,221)
Nausea (4,944)
Fatigue (3,597)
Decreased appetite (3,126)
Diarrhoea (3,026)
Dyspnoea (2,526)
Weight decreased (2,113)
Dizziness (2,027)
Rash (1,982)
Cough (1,692)
What Other Drugs Cause Hepatic failure?
ACETAMINOPHEN (1,392)
RIBAVIRIN (888)
CYCLOPHOSPHAMIDE (629)
METHOTREXATE (598)
BEVACIZUMAB (558)
SOFOSBUVIR (525)
RITUXIMAB (513)
VINCRISTINE (468)
DOXORUBICIN (462)
PREDNISOLONE (425)
Which PIRFENIDONE Alternatives Have Lower Hepatic failure Risk?
PIRFENIDONE vs PIRIBEDIL
PIRFENIDONE vs PIRITRAMIDE
PIRFENIDONE vs PIROXICAM
PIRFENIDONE vs PIRTOBRUTINIB
PIRFENIDONE vs PIT VIPER IMMUNE GLOBULIN ANTIVENIN