Does PONATINIB Cause Hepatic failure? 23 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 23 reports of Hepatic failure have been filed in association with PONATINIB (Iclusig). This represents 0.2% of all adverse event reports for PONATINIB.
23
Reports of Hepatic failure with PONATINIB
0.2%
of all PONATINIB reports
14
Deaths
13
Hospitalizations
How Dangerous Is Hepatic failure From PONATINIB?
Of the 23 reports, 14 (60.9%) resulted in death, 13 (56.5%) required hospitalization, and 3 (13.0%) were considered life-threatening.
Is Hepatic failure Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for PONATINIB. However, 23 reports have been filed with the FAERS database.
What Other Side Effects Does PONATINIB Cause?
Death (1,735)
Off label use (1,071)
Product dose omission issue (817)
Fatigue (687)
Rash (639)
Headache (553)
Pyrexia (542)
Nausea (466)
Hospitalisation (459)
Constipation (435)
What Other Drugs Cause Hepatic failure?
ACETAMINOPHEN (1,392)
RIBAVIRIN (888)
CYCLOPHOSPHAMIDE (629)
METHOTREXATE (598)
BEVACIZUMAB (558)
SOFOSBUVIR (525)
RITUXIMAB (513)
VINCRISTINE (468)
DOXORUBICIN (462)
PREDNISOLONE (425)
Which PONATINIB Alternatives Have Lower Hepatic failure Risk?
PONATINIB vs PONATINIB\PONATINIB
PONATINIB vs PONESIMOD
PONATINIB vs PORACTANT ALFA
PONATINIB vs PORFIMER
PONATINIB vs POSACONAZOLE