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Important: This site presents data from the FDA Adverse Event Reporting System (FAERS). A report does not mean the drug caused the event. Full disclaimer.

Does PONATINIB Cause Hepatic necrosis? 5 Reports in FDA Database

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According to the FDA Adverse Event Reporting System (FAERS), 5 reports of Hepatic necrosis have been filed in association with PONATINIB (Iclusig). This represents 0.1% of all adverse event reports for PONATINIB.

5
Reports of Hepatic necrosis with PONATINIB
0.1%
of all PONATINIB reports
5
Deaths
1
Hospitalizations

How Dangerous Is Hepatic necrosis From PONATINIB?

Of the 5 reports, 5 (100.0%) resulted in death, 1 (20.0%) required hospitalization, and 1 (20.0%) were considered life-threatening.

Is Hepatic necrosis Listed in the Official Label?

This adverse event is not currently listed in the official FDA drug label for PONATINIB. However, 5 reports have been filed with the FAERS database.

What Other Side Effects Does PONATINIB Cause?

Death (1,735) Off label use (1,071) Product dose omission issue (817) Fatigue (687) Rash (639) Headache (553) Pyrexia (542) Nausea (466) Hospitalisation (459) Constipation (435)

What Other Drugs Cause Hepatic necrosis?

ACETAMINOPHEN (216) CYCLOPHOSPHAMIDE (83) PREDNISONE (78) VENLAFAXINE (69) TACROLIMUS (67) MYCOPHENOLATE MOFETIL (61) METHOTREXATE (55) METHYLPREDNISOLONE (55) SOMATROPIN (50) DIMETHYL SULFONE (49)

Which PONATINIB Alternatives Have Lower Hepatic necrosis Risk?

PONATINIB vs PONATINIB\PONATINIB PONATINIB vs PONESIMOD PONATINIB vs PORACTANT ALFA PONATINIB vs PORFIMER PONATINIB vs POSACONAZOLE

Related Pages

PONATINIB Full Profile All Hepatic necrosis Reports All Drugs Causing Hepatic necrosis PONATINIB Demographics