Does PROCARBAZINE Cause Hepatic failure? 13 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 13 reports of Hepatic failure have been filed in association with PROCARBAZINE (Matulane). This represents 0.2% of all adverse event reports for PROCARBAZINE.
13
Reports of Hepatic failure with PROCARBAZINE
0.2%
of all PROCARBAZINE reports
5
Deaths
10
Hospitalizations
How Dangerous Is Hepatic failure From PROCARBAZINE?
Of the 13 reports, 5 (38.5%) resulted in death, 10 (76.9%) required hospitalization, and 6 (46.2%) were considered life-threatening.
Is Hepatic failure Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for PROCARBAZINE. However, 13 reports have been filed with the FAERS database.
What Other Side Effects Does PROCARBAZINE Cause?
Nausea (1,029)
Fatigue (890)
Vomiting (375)
Neutropenia (311)
Off label use (301)
Constipation (274)
Platelet count decreased (246)
White blood cell count decreased (229)
Headache (222)
Acute myeloid leukaemia (195)
What Other Drugs Cause Hepatic failure?
ACETAMINOPHEN (1,392)
RIBAVIRIN (888)
CYCLOPHOSPHAMIDE (629)
METHOTREXATE (598)
BEVACIZUMAB (558)
SOFOSBUVIR (525)
RITUXIMAB (513)
VINCRISTINE (468)
DOXORUBICIN (462)
PREDNISOLONE (425)
Which PROCARBAZINE Alternatives Have Lower Hepatic failure Risk?
PROCARBAZINE vs PROCHLORPERAZINE
PROCARBAZINE vs PROCHLORPERAZINE EDISYLATE
PROCARBAZINE vs PROCRIT
PROCARBAZINE vs PROCYCLIDINE
PROCARBAZINE vs PROGESTERONE