Does PROPOFOL Cause Hepatic necrosis? 8 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 8 reports of Hepatic necrosis have been filed in association with PROPOFOL (Propofol). This represents 0.1% of all adverse event reports for PROPOFOL.
8
Reports of Hepatic necrosis with PROPOFOL
0.1%
of all PROPOFOL reports
4
Deaths
6
Hospitalizations
How Dangerous Is Hepatic necrosis From PROPOFOL?
Of the 8 reports, 4 (50.0%) resulted in death, 6 (75.0%) required hospitalization, and 5 (62.5%) were considered life-threatening.
Is Hepatic necrosis Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for PROPOFOL. However, 8 reports have been filed with the FAERS database.
What Other Side Effects Does PROPOFOL Cause?
Drug ineffective (1,627)
Anaphylactic shock (1,494)
Hypotension (1,388)
Off label use (889)
Anaphylactic reaction (862)
Cardiac arrest (758)
Bradycardia (470)
Tachycardia (464)
Propofol infusion syndrome (420)
Foetal exposure during pregnancy (389)
What Other Drugs Cause Hepatic necrosis?
ACETAMINOPHEN (216)
CYCLOPHOSPHAMIDE (83)
PREDNISONE (78)
VENLAFAXINE (69)
TACROLIMUS (67)
MYCOPHENOLATE MOFETIL (61)
METHOTREXATE (55)
METHYLPREDNISOLONE (55)
SOMATROPIN (50)
DIMETHYL SULFONE (49)
Which PROPOFOL Alternatives Have Lower Hepatic necrosis Risk?
PROPOFOL vs PROPOXYPHENE
PROPOFOL vs PROPOXYPHENE/ACETAMINOPHEN
PROPOFOL vs PROPRANOLOL
PROPOFOL vs PROPRANOLOL\PROPRANOLOL
PROPOFOL vs PROPYLENE GLYCOL