Does PYRAZINAMIDE Cause Pancytopenia? 62 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 62 reports of Pancytopenia have been filed in association with PYRAZINAMIDE (Pyrazinamide). This represents 1.1% of all adverse event reports for PYRAZINAMIDE.
62
Reports of Pancytopenia with PYRAZINAMIDE
1.1%
of all PYRAZINAMIDE reports
28
Deaths
33
Hospitalizations
How Dangerous Is Pancytopenia From PYRAZINAMIDE?
Of the 62 reports, 28 (45.2%) resulted in death, 33 (53.2%) required hospitalization, and 18 (29.0%) were considered life-threatening.
Is Pancytopenia Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for PYRAZINAMIDE. However, 62 reports have been filed with the FAERS database.
What Other Side Effects Does PYRAZINAMIDE Cause?
Drug-induced liver injury (588)
Drug reaction with eosinophilia and systemic symptoms (492)
Paradoxical drug reaction (407)
Vomiting (307)
Pyrexia (301)
Drug ineffective (298)
Off label use (288)
Hepatotoxicity (279)
Drug resistance (269)
Nausea (251)
What Other Drugs Cause Pancytopenia?
METHOTREXATE (5,377)
CYCLOPHOSPHAMIDE (3,351)
CARBOPLATIN (2,910)
RITUXIMAB (2,400)
LENALIDOMIDE (2,259)
DOXORUBICIN (2,212)
VINCRISTINE (2,180)
ETOPOSIDE (2,129)
DEXAMETHASONE (2,053)
PREDNISONE (1,743)
Which PYRAZINAMIDE Alternatives Have Lower Pancytopenia Risk?
PYRAZINAMIDE vs PYRIDOSTIGMINE
PYRAZINAMIDE vs PYRIDOXINE
PYRAZINAMIDE vs PYRIDOXINE\THIAMINE
PYRAZINAMIDE vs PYRIMETHAMINE
PYRAZINAMIDE vs PYROTINIB