Does PYRAZINAMIDE Cause Sepsis? 65 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 65 reports of Sepsis have been filed in association with PYRAZINAMIDE (Pyrazinamide). This represents 1.2% of all adverse event reports for PYRAZINAMIDE.
65
Reports of Sepsis with PYRAZINAMIDE
1.2%
of all PYRAZINAMIDE reports
51
Deaths
42
Hospitalizations
How Dangerous Is Sepsis From PYRAZINAMIDE?
Of the 65 reports, 51 (78.5%) resulted in death, 42 (64.6%) required hospitalization, and 22 (33.8%) were considered life-threatening.
Is Sepsis Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for PYRAZINAMIDE. However, 65 reports have been filed with the FAERS database.
What Other Side Effects Does PYRAZINAMIDE Cause?
Drug-induced liver injury (588)
Drug reaction with eosinophilia and systemic symptoms (492)
Paradoxical drug reaction (407)
Vomiting (307)
Pyrexia (301)
Drug ineffective (298)
Off label use (288)
Hepatotoxicity (279)
Drug resistance (269)
Nausea (251)
What Other Drugs Cause Sepsis?
RITUXIMAB (4,043)
CYCLOPHOSPHAMIDE (4,041)
METHOTREXATE (3,933)
ADALIMUMAB (3,169)
DEXAMETHASONE (3,150)
LENALIDOMIDE (2,956)
VINCRISTINE (2,791)
DOXORUBICIN (2,740)
PREDNISONE (2,634)
PREDNISOLONE (2,281)
Which PYRAZINAMIDE Alternatives Have Lower Sepsis Risk?
PYRAZINAMIDE vs PYRIDOSTIGMINE
PYRAZINAMIDE vs PYRIDOXINE
PYRAZINAMIDE vs PYRIDOXINE\THIAMINE
PYRAZINAMIDE vs PYRIMETHAMINE
PYRAZINAMIDE vs PYROTINIB