RASBURICASE for Hyperuricaemia: Side Effects & Safety Data
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There are 78 adverse event reports in the FDA FAERS database where RASBURICASE was used for Hyperuricaemia.
Most Reported Side Effects for RASBURICASE
| Side Effect | Reports | % | Deaths | Hosp. |
|---|---|---|---|---|
| Tumour lysis syndrome | 116 | 13.1% | 46 | 38 |
| Methaemoglobinaemia | 92 | 10.4% | 8 | 70 |
| Off label use | 90 | 10.2% | 29 | 30 |
| Product use in unapproved indication | 76 | 8.6% | 10 | 65 |
| Bacterial infection | 75 | 8.5% | 9 | 75 |
| Fungal infection | 73 | 8.3% | 7 | 73 |
| Cellulitis | 72 | 8.1% | 6 | 72 |
| Clostridium difficile colitis | 72 | 8.1% | 6 | 72 |
| Lymphoid tissue hypoplasia | 72 | 8.1% | 6 | 72 |
| Lymphopenia | 72 | 8.1% | 6 | 72 |
| Drug ineffective | 71 | 8.0% | 22 | 39 |
| Thymus hypoplasia | 70 | 7.9% | 6 | 70 |
| Disseminated aspergillosis | 67 | 7.6% | 6 | 67 |
| Cytomegalovirus viraemia | 65 | 7.3% | 6 | 65 |
| Haemolytic anaemia | 57 | 6.4% | 1 | 42 |
Other Indications for RASBURICASE
Tumour lysis syndrome (151)
Prophylaxis (107)
Product used for unknown indication (99)
Acute lymphocytic leukaemia (41)
Acute myeloid leukaemia (18)
Non-hodgkin's lymphoma (16)
Blood uric acid increased (15)
Blood uric acid (12)
Blood uric acid abnormal (12)
Premedication (12)
Other Drugs Used for Hyperuricaemia
ALLOPURINOL (3,041)
FEBUXOSTAT (1,151)
COLCHICINE (55)
FEBURIC (48)
BENZBROMARONE (25)
LESINURAD (18)
BLINDED ALLOPURINOL (12)
BLINDED FEBUXOSTAT (12)
ADENURIC (11)
IBUPROFEN (10)